The Pseudomonas aeruginosa polysaccharide PSL is a social but non-cheatable trait in biofilms
نویسندگان
چکیده
1 School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, United Kingdom 2 Department of Biology & Biochemistry, University of Bath, Claverton Down, Bath, United Kingdom 3 Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark 4 Center for Nonlinear Dynamics and Department of Physics, The University of Texas at Austin, 2515 Speedway, Stop C1610, Austin, TX 78712-1199, USA 5 School of Physics and Astronomy, University of Edinburgh, James Clerk Maxwell Building, Peter Guthrie Tait Road, Edinburgh EH9 3FD, United Kingdom 6 Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark 7 Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
منابع مشابه
The Pseudomonas aeruginosa PSL Polysaccharide Is a Social but Noncheatable Trait in Biofilms
Extracellular polysaccharides are compounds secreted by microorganisms into the surrounding environment, and they are important for surface attachment and maintaining structural integrity within biofilms. The social nature of many extracellular polysaccharides remains unclear, and it has been suggested that they could function as either cooperative public goods or as traits that provide a compe...
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Bacteria within biofilms secrete and surround themselves with an extracellular matrix, which serves as a first line of defense against antibiotic attack. Polysaccharides constitute major elements of the biofilm matrix and are implied in surface adhesion and biofilm organization, but their contributions to the resistance properties of biofilms remain largely elusive. Using a combination of stati...
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Pseudomonas aeruginosa PAO1 produces three polysaccharides, alginate, Psl, and Pel that play distinct roles in attachment and biofilm formation for monospecies biofilms. Considerably less is known about their role in the development of mixed species biofilm communities. This study has investigated the roles of alginate, Psl, and Pel during biofilm formation of P. aeruginosa in a defined and exp...
متن کاملPsl Produced by Mucoid Pseudomonas aeruginosa Contributes to the Establishment of Biofilms and Immune Evasion
Despite years of research and clinical advances, chronic pulmonary infections with mucoid Pseudomonas aeruginosa remain the primary concern for cystic fibrosis patients. Much of the research on these strains has focused on the contributions of the polysaccharide alginate; however, it is becoming evident that the neutral polysaccharide Psl also contributes to biofilm formation and the maintenanc...
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